It means step the fuck up.

“This is not on, someone tell him to hedefuckup!”

The usage of this word became popular after a viral Tik Tok video of Vusi Thembekwayo ranting about the economic situation in South Africa.

“it’s sprint time at 4:30 and ama need george and lewis to hedefuckup!”

— b a s q u i a t (@anxiousberryx) April 23, 2022